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Article

IL28B polymorphism is associated with treatment response in patients with genotype 4 chronic hepatitis C.

Journal of hepatology - 1 Mar 2012

Asselah Tarik, De Muynck Simon, Broët Philippe, Masliah-Planchon Julien, Blanluet Maud, Bièche Ivan, Lapalus Martine, Martinot-Peignoux Michelle, Lada Olivier, Estrabaud Emilie, Zhang Qian, El Ray Ahmed, Vidaud Dominique, Ripault Marie-Pierre, Boyer Nathalie, Bedossa Pierre, Valla Dominique, Vidaud Michel, Marcellin Patrick

Abstract excerpt

BACKGROUND & AIMS: Polymorphisms in the region of the interleukin (IL)28B gene have been associated with pegylated-interferon (PEG-IFN) and ribavirin treatment response mainly in genotype 1 HCV infections. However, there are few data on HCV genotype 4 (HCV-4) infection. We evaluated, in a unique well-characterized cohort of HCV-4 patients, the association of IL28B polymorphism with response to treatment or liver...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 21951981
DOI: 10.1016/j.jhep.2011.09.008

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