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Article

Interleukin-28b CC genotype predicts early treatment response and CT/TT genotypes predicts non-response in patients infected with HCV genotype 3.

Journal of medical virology - 1 Apr 2014

Gupta Abhishak Chander, Trehanpati Nirupma, Sukriti Sukriti, Hissar Syed, Midha Vandana, Sood Ajit, Sarin Shiv K

Abstract excerpt

Response to antiviral therapy for hepatitis C virus (HCV) depends upon the genotype and host immune response. IL28b gene mutations have been shown to modulate host antiviral immune response against genotype 1. However, the predictive value of IL28b polymorphism in genotype 3 HCV patients is largely unknown. The association of IL28b polymorphism with virological response was studied in 356 patients with genotype 3...

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PMID: 24415442
DOI: 10.1002/jmv.23876

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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