Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Novel nucleotide changes in mutational analysis of mitochondrial 12SrRNA gene in patients with nonsyndromic and aminoglycoside-induced hearing loss.

Molecular biology reports - 1 Mar 2013

Dowlati Mohammad Ali, Derakhshandeh-Peykar Pupak, Houshmand Massoud, Farhadi Mohammad, Shojaei Azadeh, Fallah Masoomeh, Mohammadi Esmaiil, Tajdini Ardavan, Arastoo Shima, Tavakkoly-Bazzaz Javad

Abstract excerpt

Mitochondria have essential role in cellular energy metabolism and defects in their function lead to many metabolic diseases. Mitochondrial DNA (mtDNA) mutations have been associated with number diseases such as nonsyndromic and aminoglycoside-induced hearing loss. Mutational screening of entire 12SrRNA and tRNA (ser (UCN)) genes in 107 unrelated Iranian patients with amino glycoside-induced and nonsyndromic...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aminoglycosides
Share to Child, Preschool

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Mutational Analysis

Share to Genes, Mitochondrial

Share to Haplotypes

Share to Hearing Loss

Share to RNA, Ribosomal

Share to Young Adult

Source

Identifiers

PMID: 23242658
DOI: 10.1007/s11033-012-2355-8

Genes

UCN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Novel nucleotide changes in mutational analysis of mitochondrial 12SrRNA gene in patients with nonsyndromic and aminoglycoside-induced hearing loss.PMID 23242658Read ↗

The role of mitochondrial DNA mutations in hearing loss.Semantic proximity Read ↗

[Mitochondrial DNA mutations and aminoglycoside antibiotics and hearing loss].Semantic proximity Read ↗

Mitochondrial 12S rRNA variants in 1642 Han Chinese pediatric subjects with aminoglycoside-induced and nonsyndromic hearing loss.Semantic proximity Read ↗

Genetics of aminoglycoside-induced and prelingual non-syndromic mitochondrial hearing impairment: a review.Semantic proximity Read ↗

Mitochondrial 12S rRNA mutations associated with aminoglycoside ototoxicity.Semantic proximity Read ↗

Screening for mitochondrial 12S rRNA C1494T mutation in 655 patients with non-syndromic hearing loss: An observational study.Semantic proximity Read ↗

[Mitochondrial 12S rRNA variants studies in 456 subjects with hearing loss in seven schools for deaf and mutes in Zhejiang province].Semantic proximity Read ↗

Frequency and spectrum of mitochondrial 12S rRNA variants in 440 Han Chinese hearing impaired pediatric subjects from two otology clinics.Semantic proximity Read ↗

Maternally transmitted aminoglycoside-induced and non-syndromic hearing loss caused by the 1494C > T mutation in the mitochondrial 12S rRNA gene in two Chinese families.Semantic proximity Read ↗

[Function study of non-syndromic deafness associated mitochondrial 12S rRNA A839G mutation].Semantic proximity Read ↗

Study of modifiers factors associated to mitochondrial mutations in individuals with hearing impairment.Semantic proximity Read ↗

[Mitochondrial 12S rRNA gene A827G in two pedigrees with nonsyndromic deafness].Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.