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Article

[APOE gene polymorphisms associated with Down syndrome in Colombian populations].

Biomedica : revista del Instituto Nacional de Salud - 1 Jun 2012

Rengifo Lucero, Gaviria Duverney, Serrano Herman

Abstract excerpt

Introduction.Gene APOEε4 allele polymorphisms have been examined in Down syndrome because of the relationship between (a) the E4 isoform and (b) the type of Alzheimer's dementia that appears in individuals with Down syndrome. This isoform is considered a risk factor for Alzheimer's disease development and has been associated with early death in Down syndrome. Objectives. The polymorphisms in the APOE gene were...

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Source

Identifiers

PMID: 23242296
DOI: 10.1590/S0120-41572012000300010

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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