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Article

Targeting late SV40 factor: is the achilles heel of hepatocarcinogenesis revealed?

World journal of gastroenterology - 14 Dec 2012

Shlomai Amir

Abstract excerpt

Hepatocellular carcinoma (HCC) is a dreadful cancer and a major cause of death among patients with chronic liver disease and cirrhosis. The apparent alterations in a diversity of intracellular pathways found in HCC has set the rational for developing molecular-directed drugs that simultaneously inhibit multiple pathways, such as the multi-kinase inhibitor Sorafenib. However, recently this concept has been...

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Identifiers

PMID: 23239907
DOI: 10.3748/wjg.v18.i46.6709
PMCID: PMC3520158

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Source receipt: pubmed, retrieved 7 Sept 2026.

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Targeting late SV40 factor: is the achilles heel of hepatocarcinogenesis revealed?PMID 23239907Read ↗

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