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Article

Genetic variation at the TPH2 gene influences impulsivity in addition to eating disorders.

Behavior genetics - 1 Jan 2013

Slof-Op't Landt Margarita C T, Bartels Meike, Middeldorp Christel M, van Beijsterveldt Catherina E M, Slagboom P Eline, Boomsma Dorret I, van Furth Eric F, Meulenbelt Ingrid

Abstract excerpt

Genes are involved in eating disorders (EDs) and self-induced vomiting (SV), a key symptom of different types of EDs. Perfectionism and impulsivity are potential risk factors for EDs. TPH2 (tryptophan hydroxylase 2) SNP rs1473473 was previously associated with anorexia nervosa and EDs characterized by SV. Could perfectionism or impulsivity be underlying the association between rs1473473 and EDs? Genetic...

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Source

Identifiers

PMID: 23239044
DOI: 10.1007/s10519-012-9569-3

Genes

TPH2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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