Article
Association study in eating disorders: TPH2 associates with anorexia nervosa and self-induced vomiting.
Genes, brain, and behavior - 1 Mar 2011
Slof-Op 't Landt M C T, Meulenbelt I, Bartels M, Suchiman E, Middeldorp C M, Houwing-Duistermaat J J, van Trier J, Onkenhout E J, Vink J M, van Beijsterveldt C E M, Brandys M K, Sanders N, Zipfel S, Herzog W, Herpertz-Dahlmann B, Klampfl K, Fleischhaker C, Zeeck A, de Zwaan M, Herpertz S, Ehrlich S, van Elburg A A, Adan R A H, Scherag S, Hinney A, Hebebrand J, Boomsma D I, van Furth E F, Slagboom P E
Abstract excerpt
Twin studies suggest that genetic factors play a substantial role in anorexia nervosa (AN) and self-induced vomiting (SV), a key symptom that is shared among different types of eating disorders (EDs). We investigated the association of 25 single nucleotide polymorphisms (SNPs), capturing 71-91% of the common variance in candidate genes, stathmin (STMN1), serotonin receptor 1D (HTR1D), tryptophan hydroxylase 2...
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