Article
The impact of copy number deletions on general cognitive ability and ventricle size in patients with schizophrenia and healthy control subjects.
Biological psychiatry - 15 Mar 2013
Yeo Ronald A, Gangestad Steven W, Liu Jingyu, Ehrlich Stefan, Thoma Robert J, Pommy Jessica, Mayer Andrew R, Schulz S Charles, Wassink Thomas H, Morrow Eric M, Bustillo Juan R, Sponheim Scott R, Ho Beng-Choon, Calhoun Vince D
Abstract excerpt
BACKGROUND: General cognitive ability is usually lower in individuals with schizophrenia, partly due to genetic influences. However, the specific genetic features related to general cognitive ability are poorly understood. Individual variation in a specific type of mutation, uncommon genetic deletions, has recently been linked with both general cognitive ability and risk for schizophrenia. METHODS: We derived...
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