Article
Phenotype and functions of natural killer cells in critically-ill septic patients.
PloS one - 1 Jan 2012
Forel Jean-Marie, Chiche Laurent, Thomas Guillemette, Mancini Julien, Farnarier Catherine, Cognet Céline, Guervilly Christophe, Daumas Aurélie, Vély Frédéric, Xéridat François, Vivier Eric, Papazian Laurent
Abstract excerpt
RATIONALE: Natural killer cells, as a major source of interferon-γ, contribute to the amplification of the inflammatory response as well as to mortality during severe sepsis in animal models. OBJECTIVE: We studied the phenotype and functions of circulating NK cells in critically-ill septic patients. METHODS: Blood samples were taken <48 hours after admission from 42 ICU patients with severe sepsis (n = 15) or...
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