Depletion of NK cells in a murine polytrauma model is associated with improved outcome and a modulation of the inflammatory response.

Abstract excerpt

Sepsis and associated diseases such as systemic inflammatory response syndrome and multiple organ dysfunction syndrome represent common posttraumatic complications on intensive care units induced by a variety of body defense mechanisms. Natural killer (NK) cells are part of the innate immune system. They are thought to play an important role in the development of such syndromes by interplay with other immune cell...

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