Article
Lack of BRAF V600E protein expression in primary central nervous system lymphoma.
Applied immunohistochemistry & molecular morphology : AIMM - 1 Jul 2013
Berghoff Anna S, Capper David, Preusser Matthias
Abstract excerpt
BACKGROUND: Mutations in the v-raf murine sarcoma viral oncogenes homolog B1 (BRAF), most commonly of the V600E type, are present in a variety of human malignancies including malignant melanoma, papillary thyroid cancers, and hairy-cell leukemia and specific therapeutically active BRAF inhibitors exist. We aimed to investigate BRAF V600E protein expression in primary central nervous system lymphoma (PCNSL)....
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