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Article

The -2T/C polymorphism in the adrenocorticotropin receptor gene affects stress perception of patients with alopecia areata.

International journal of dermatology - 1 Apr 2013

Guo Hong-Wei, Guo Hong, Li Ke-Shen, Wu Jiang, Yang Shao-Yan, Liu Bao-Heng, Hao Fei, Bai Yun

Abstract excerpt

BACKGROUND: Altered hypothalamic-pituitary-adrenal (HPA) axis response involved in the pathogenesis of stress-associated alopecia areata (AA) has been reported. A novel polymorphism -2T>C of the adrenocorticotropin receptor (ACTHR) can result in an insufficient HPA response to stress; therefore, the functional polymorphism may underlie a role in stress-associated AA. OBJECTIVE: To investigate the relationship...

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Source

Identifiers

PMID: 23231661
DOI: 10.1111/j.1365-4632.2012.05749.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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