Article
Salivary cortisol in unaffected twins discordant for affective disorder.
Psychiatry research - 15 Dec 2008
Vinberg Maj, Bennike Bente, Kyvik Kirsten Ohm, Andersen Per Kragh, Kessing Lars Vedel
Abstract excerpt
Dysfunction in the hypothalamic-pituitary-adrenal (HPA) axis has been proposed as a biological endophenotype for affective disorders. In the present study the hypothesis that a high genetic liability to affective disorder is associated with higher cortisol levels was tested in a cross-sectional high-risk study. Healthy monozygotic (MZ) and dizygotic (DZ) twins with (High-Risk twins) and without (Low-Risk twins) a...
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