Article
Lack of Association between the TSPAN18 Gene and Schizophrenia Based on New Data from Han Chinese and a Meta-Analysis.
International journal of molecular sciences - 26 May 2015
Zhang Bao, Li Da-Xu, Lu Ning, Fan Qian-Rui, Li Wen-Hao, Feng Zu-Fei
Abstract excerpt
Tetraspanin-18 (TSPAN18) potentially plays a role in the calcium signaling that is associated with dopamine-induced cortical neuron apoptosis and is considered to be an important mechanism in the pathogenesis of schizophrenia (SCZ). Furthermore, a genome-wide association study (GWAS) identified TSPAN18 as a possible susceptibility gene for SCZ. To validate these findings and reveal the effects of different...
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