Article
Replication study confirms link between TSPAN18 mutation and schizophrenia in Han Chinese.
PloS one - 1 Jan 2013
Yuan Jianmin, Jin Chunhui, Qin Hai-De, Wang Jidong, Sha Weiwei, Wang Mingzhong, Zhang Yunbiao, Zhang Fuquan, Li Jijiang, Li Jianfeng, Yu Shui, Qi Shuguang, Shugart Yin Yao
Abstract excerpt
Schizophrenia (SCZ) is a severe psychiatric disorder associated with many different risk factors, both genetic and environmental. A recent genome-wide association study (GWAS) of Han Chinese identified three single-nucleotide polymorphisms (SNPs rs11038167, rs11038172, and rs835784) in the tetraspanins gene TSPAN18 as possible susceptibility loci for schizophrenia. Hoping to validate these findings, we conducted...
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