Article
SLC gene-modified dendritic cells mediate T cell-dependent anti-gastric cancer immune responses in vitro.
Oncology reports - 1 Feb 2013
Xue Gang, Cheng Ying, Ran Feng, Li Xianhui, Huang Tao, Yang Yong, Zhang Yanbiao
Abstract excerpt
Dendritic cells (DCs) are potent professional antigen-presenting cells (APCs) with the ability to prime naïve T cells, and play an important role in the initiation and regulation of immune responses. In this study, we constructed a recombinant adenovirus carrying the SLC gene (Ad-SLC), and detected the biological effects of Ad-SLC-modified DCs as an adjuvant for the initiation of gastric cancer immune responses....
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