Article
Analyzing HLA-G polymorphisms in children from women with scleroderma.
Human immunology - 1 Apr 2013
Picard Christophe, Di Cristofaro Julie, Azzouz Doua F, Kanaan Sami B, Roudier Jean, Lambert Nathalie C
Abstract excerpt
Embryos during pregnancy and organs during transplantation, express high levels of soluble HLA-G (sHLA-G) molecules for successful implantation and protection against maternal immune cells or recipient's cells. We and others have shown that women with scleroderma (SSc) carry cells/DNA arising from pregnancy, so-called fetal microchimerism (Mc) more often and in higher quantities than healthy women decades after...
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