Article
Cutting edge: persistent fetal microchimerism in T lymphocytes is associated with HLA-DQA1*0501: implications in autoimmunity.
Journal of immunology (Baltimore, Md. : 1950) - 1 Jun 2000
Lambert N C, Evans P C, Hashizumi T L, Maloney S, Gooley T, Furst D E, Nelson J L
Abstract excerpt
The host's MHC genotype plays a critical role in susceptibility to autoimmune diseases. We previously proposed that persistent fetal microchimerism from pregnancy contributes to the pathogenesis of autoimmune diseases such as scleroderma. In the current study, we investigated whether the specific host MHC genotype is associated with persistent microchimerism among T lymphocytes in women with scleroderma and in...
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