Article
Soluble HLA-G Expression Inversely Correlates With Fetal Microchimerism Levels in Peripheral Blood From Women With Scleroderma.
Frontiers in immunology - 1 Jan 2018
Di Cristofaro Julie, Karlmark Karlin R, Kanaan Sami B, Azzouz Doua F, El Haddad Marina, Hubert Lucas, Farge-Bancel Dominique, Granel Brigitte, Harlé Jean Robert, Hachulla Eric, Pardoux Etienne, Roudier Jean, Picard Christophe, Lambert Nathalie C
Abstract excerpt
Women with scleroderma (SSc) maintain significantly higher quantities of persisting fetal microchimerism (FMc) from complete or incomplete pregnancies in their peripheral blood compared to healthy women. The non-classical class-I human leukocyte antigen (HLA) molecule HLA-G plays a pivotal role for the implantation and maintenance of pregnancy and has often been investigated in offspring from women with pregnancy...
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