Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Derivation of HLA types from shotgun sequence datasets

10 Dec 2012

Abstract excerpt

The human leukocyte antigen (HLA) is key to many aspects of human physiology and medicine. All current sequence-based HLA typing methodologies are targeted approaches requiring the amplification of specific HLA gene segments. Whole genome, exome and transcriptome shotgun sequencing can generate prodigious data but due to the complexity of HLA loci these data have not been immediately informative regarding HLA...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cytomegalovirus and herpesvirus research
Share to Herpesvirus Infections and Treatments
Share to Toxoplasma gondii Research Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 23228053
DOI: 10.1186/gm396

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Derivation of HLA types from shotgun sequence datasetsPMID 23228053Read ↗

Comprehensive HLA Typing from a Current Allele Database Using Next-Generation Sequencing Data.Semantic proximity Read ↗

HLA informatics. Accessing HLA sequences from sequence databases.Semantic proximity Read ↗

Comprehensive HLA Typing from a Current Allele Database Using Next-Generation Sequencing Data.Semantic proximity Read ↗

HLAProfiler utilizes k-mer profiles to improve HLA calling accuracy for rare and common alleles in RNA-seq data.Semantic proximity Read ↗

Next-Generation Sequencing of the HLA locus: Methods and impacts on HLA typing, population genetics and disease association studies.Semantic proximity Read ↗

Targeted analysis of polymorphic loci from low-coverage shotgun sequence data allows accurate genotyping of HLA genes in historical human populations.Semantic proximity Read ↗

High-Definition Genomic Analysis of HLA Genes Via Comprehensive HLA Allele Genotyping.Semantic proximity Read ↗

HLA-HD: An accurate HLA typing algorithm for next-generation sequencing data.Semantic proximity Read ↗

Benchmarking freely available human leukocyte antigen typing algorithms across varying genes, coverages and typing resolutionsSemantic proximity Read ↗

Bioinformatics Strategies, Challenges, and Opportunities for Next Generation Sequencing-Based HLA GenotypingSemantic proximity Read ↗

Systematic comparative study of computational methods for HLA typing from next-generation sequencing.Semantic proximity Read ↗

Easy-HLA: a validated web application suite to reveal the full details of HLA typing.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.