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Article

Cell specific CD44 expression in breast cancer requires the interaction of AP-1 and NFκB with a novel cis-element.

PloS one - 1 Jan 2012

Smith Shannon M, Cai Li

Abstract excerpt

Breast cancers contain a heterogeneous population of cells with a small percentage that possess properties similar to those found in stem cells. One of the widely accepted markers of breast cancer stem cells (BCSCs) is the cell surface marker CD44. As a glycoprotein, CD44 is involved in many cellular processes including cell adhesion, migration and proliferation, making it pro-oncogenic by nature. CD44 expression...

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Identifiers

PMID: 23226410
DOI: 10.1371/journal.pone.0050867
PMCID: PMC3511339

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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