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Article

TgCDPK3 Regulates Calcium-Dependent Egress of Toxoplasma gondii from Host Cells

4 Dec 2012

Abstract excerpt

The phylum Apicomplexa comprises a group of obligate intracellular parasites of broad medical and agricultural significance, including Toxoplasma gondii and the malaria-causing Plasmodium spp. Key to their parasitic lifestyle is the need to egress from an infected cell, actively move through tissue, and reinvade another cell, thus perpetuating infection. Ca(2+)-mediated signaling events modulate key steps...

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PMID: 23226109
DOI: 10.1371/journal.ppat.1003066

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