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Article

Apoptosis in Down's syndrome: lessons from studies of human and mouse models.

Apoptosis : an international journal on programmed cell death - 1 Feb 2013

Rueda Noemí, Flórez Jesús, Martínez-Cué Carmen

Abstract excerpt

Down syndrome (DS) is the most common chromosomal abnormality in humans. DS is characterized by a number of phenotypes, including the development of Alzheimer's disease-like pathology and immunological, hematological and cardiovascular alterations. Apoptosis or programmed cell death is physiologically involved in development and aging, as well as in numerous pathological processes. Altered apoptosis has been...

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Identifiers

PMID: 23224708
DOI: 10.1007/s10495-012-0785-3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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