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Article

Replication of GWAS-identified neuroblastoma risk loci strengthens the role of BARD1 and affirms the cumulative effect of genetic variations on disease susceptibility.

Carcinogenesis - 1 Mar 2013

Capasso Mario, Diskin Sharon J, Totaro Francesca, Longo Luca, De Mariano Marilena, Russo Roberta, Cimmino Flora, Hakonarson Hakon, Tonini Gian Paolo, Devoto Marcella, Maris John M, Iolascon Achille

Abstract excerpt

Several neuroblastoma (NB) susceptibility loci have been identified within LINC00340, BARD1, LMO1, DUSP12, HSD17B12, DDX4, IL31RA, HACE1 and LIN28B by genome-wide association (GWA) studies including European American individuals. To validate and comprehensively evaluate the impact of the identified NB variants on disease risk and phenotype, we analyzed 16 single nucleotide polymorphisms (SNPs) in an Italian...

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Source

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Identifiers

PMID: 23222812
DOI: 10.1093/carcin/bgs380
PMCID: PMC3716226

Genes

BARD1
DDX4
DUSP12
LMO1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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