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Article

Fine mapping of 2q35 high-risk neuroblastoma locus reveals independent functional risk variants and suggests full-length BARD1 as tumor-suppressor.

International journal of cancer - 1 Dec 2018

Cimmino Flora, Avitabile Marianna, Diskin Sharon J, Vaksman Zalman, Pignataro Piero, Formicola Daniela, Cardinale Antonella, Testori Alessandro, Koster Jan, de Torres Carmen, Devoto Marcella, Maris John M, Iolascon Achille, Capasso Mario

Abstract excerpt

A previous genome-wide association study (GWAS) identified common variation at the BARD1 locus as being highly associated with susceptibility to high-risk neuroblastoma, but the mechanisms underlying this association have been not extensively investigated. Here, we performed a fine mapping analysis of BARD1 locus (2q35) using GWAS data from 556 high-risk neuroblastoma patients and 2,575 controls of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 30132831
DOI: 10.1002/ijc.31822
PMCID: PMC6258207

Genes

BARD1
HSF1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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