Prioritization and Meta-analysis of regulatory SNPs identified IL6, TGFB1, TLR9 and MMP7 as significantly associated with cervical cancer.

doi:10.1016/j.cyto.2022.155954

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Article

Prioritization and Meta-analysis of regulatory SNPs identified IL6, TGFB1, TLR9 and MMP7 as significantly associated with cervical cancer.

Cytokine - 1 Sept 2022

Das Agneesh Pratim, Chopra Meenu, Agarwal Subhash M

Abstract excerpt

Cervical cancer is a leading women cancer globally with respect to both incidence and mortality. Its increased risk has been linked with HPV infection and genetic variations like single nucleotide polymorphisms (SNPs). Although, studies have been published which evaluates the effect of SNPs in a few candidate genes, however the role of number of regulatory SNPs (rSNPs) in cervical cancer is not available. As...

Topics

Female
Genetic Predisposition to Disease
Humans
Interleukin-6
Matrix Metalloproteinase 7
Polymorphism, Single Nucleotide
Toll-Like Receptor 9
Transforming Growth Factor beta1
Uterine Cervical Neoplasms

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Identifiers

PMID: 35810505
DOI: 10.1016/j.cyto.2022.155954

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