Article
Status of TIM-1 exon 4 haplotypes and CD4+T cell counts in HIV-1 seroprevalent North Indians.
Human immunology - 1 Feb 2013
Sharma Gaurav, Ohtani Hitoshi, Kaur Gurvinder, Naruse Taeko K, Sharma S K, Vajpayee Madhu, Kimura Akinori, Mehra Narinder
Abstract excerpt
The TIM (T cell/transmembrane, immunoglobulin and mucin) proteins are crucial regulators of Th1/Th2 immune responses and have been implicated in several diseases including HIV-1/AIDS. The TIM1 exon 4 that codes for mucin domain is highly diverse, with sequence variants associated with varying phenotypes. In this study, TIM1 exon 4 was sequenced among 227 HIV-1 seroprevalent and 288 healthy non infected...
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