Article
TIM1 haplotype may control the disease progression to AIDS in a HIV-1-infected female cohort in Thailand.
AIDS (London, England) - 17 Jul 2010
Wichukchinda Nuanjun, Nakajima Toshiaki, Saipradit Nongluk, Nakayama Emi E, Ohtani Hitoshi, Rojanawiwat Archawin, Pathipvanich Panita, Ariyoshi Koya, Sawanpanyalert Pathom, Shioda Tatsuo, Kimura Akinori
Abstract excerpt
OBJECTIVE: To investigate association of TIM1 sequence variations with HIV/AIDS progression. INTRODUCTION: : HIV-1 infected individuals have wide variations in disease progression including AIDS. T cell immunoglobulin and mucin 1 (TIM1) is a cell surface protein involved in the regulation of Th1/Th2 immune response. MATERIALS AND METHODS: We sequenced the highly polymorphic exon 4 of TIM1 from 246 individuals of...
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