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Article

Insertion sequence disruption of adeR and ciprofloxacin resistance caused by efflux pumps and gyrA and parC mutations in Acinetobacter baumannii.

International journal of antimicrobial agents - 1 Feb 2013

Lopes B S, Amyes S G B

Abstract excerpt

Acinetobacter baumannii is a pathogenic bacterium responsible for a wide range of infections in immunocompromised patients. This study examined the role of insertional inactivation of the adeR gene and its effect on adeABC gene expression along with characterisation of the gyrA and parC mutations involved in ciprofloxacin resistance in three A. baumannii clinical isolates and their derivatives. Primers designed...

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Identifiers

PMID: 23217848
DOI: 10.1016/j.ijantimicag.2012.08.012

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