Article
Disruption of adeB gene has a greater effect on resistance to meropenems than adeA gene in Acinetobacter spp. isolated from University Malaya Medical Centre.
Singapore medical journal - 1 Aug 2009
Wong E W, Yusof M Y Mohd, Mansor M Bt, Anbazhagan D, Ong S Y, Sekaran S D
Abstract excerpt
INTRODUCTION: The AdeABC pump of Acinetobacter spp. confers resistance to various antibiotic classes. This pump is composed of the AdeA, AdeB, and AdeC proteins where AdeB is a member of the resistance-nodulation-division efflux pump superfamily. The adeA, adeB, and adeC genes are contiguous and adjacent to adeS and adeR, which are transcribed in the opposite direction and which specify proteins homologous to...
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