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Article

Deletion of TnAbaR23 results in both expected and unexpected antibiogram changes in a multidrug-resistant Acinetobacter baumannii strain.

Antimicrobial agents and chemotherapy - 1 Apr 2012

Kochar Mandira, Crosatti Marialuisa, Harrison Ewan M, Rieck Barbara, Chan Jacqueline, Constantinidou Chrystala, Pallen Mark, Ou Hong-Yu, Rajakumar Kumar

Abstract excerpt

Since the 2006 discovery of the Acinetobacter baumannii strain AYE AbaR1 resistance island, similar elements have been reported in numerous members of this species. As AbaR1 is distantly related to Tn7, we have renamed it TnAbaR1. TnAbaR transposons are known to carry multiple antibiotic resistance- and efflux-associated genes, although none have been experimentally studied en bloc. We deleted the TnAbaR...

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Identifiers

PMID: 22290963
DOI: 10.1128/AAC.05334-11
PMCID: PMC3318347

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