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Article

The LEDGF/p75 integrase interaction, a novel target for anti-HIV therapy

7 Dec 2012

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 23217620
DOI: 10.1016/j.virol.2012.09.033

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Related research

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Research trail→

Click a neighbor to travelStep 1 · 12 closest

The LEDGF/p75 integrase interaction, a novel target for anti-HIV therapyPMID 23217620Read ↗

Overexpression of the Lens Epithelium-Derived Growth Factor/p75 Integrase Binding Domain Inhibits Human Immunodeficiency Virus ReplicationSemantic proximity Read ↗

Structural basis for HIV‐1 DNA integration in the human genome, role of the LEDGF/P75 cofactorSemantic proximity Read ↗

Virus evolution reveals an exclusive role for LEDGF/p75 in chromosomal tethering of HIV.Semantic proximity Read ↗

Transient and Stable Knockdown of the Integrase Cofactor LEDGF/p75 Reveals Its Role in the Replication Cycle of Human Immunodeficiency VirusSemantic proximity Read ↗

LEDGIN-mediated Inhibition of Integrase–LEDGF/p75 Interaction Reduces Reactivation of Residual Latent HIVSemantic proximity Read ↗

An Essential Role for LEDGF/p75 in HIV IntegrationSemantic proximity Read ↗

Cellular Cofactors of Lentiviral Integrase: From Target Validation to Drug DiscoverySemantic proximity Read ↗

Characterization of LEDGF/p75 genetic variants and association with HIV-1 disease progression.Semantic proximity Read ↗

Insight in HIV Integration Site Selection Provides a Block-and-Lock Strategy for a Functional Cure of HIV InfectionSemantic proximity Read ↗

Lens Epithelium-derived Growth Factor/p75 Interacts with the Transposase-derived DDE Domain of PogZSemantic proximity Read ↗

Integrase Mutants Defective for Interaction with LEDGF/p75 Are Impairedin Chromosome Tethering and HIV-1ReplicationSemantic proximity Read ↗

Inhibitors of the Interactions between HIV‐1 IN and the Cofactor LEDGF/p75Semantic proximity Read ↗

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