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Article

Structural analysis of the inhibition of APRIL by TACI and BCMA through molecular dynamics simulations.

Journal of molecular graphics & modelling - 1 Feb 2013

González-Mendióroz Maite, Alvarez-Vázquez Ana Belén, Rubio-Martinez Jaime

Abstract excerpt

APRIL (a proliferation-inducing ligand) is a member of the tumour necrosis factor (TNF) superfamily that binds the receptors (TNFRs) TACI and BCMA. Since it was discovered, a great amount of evidence has been reported about the involvement of APRIL in autoimmune diseases including systemic lupus erythematosus (SLE), rheumatoid arthritis (RA), Sjögren's syndrome (SS) and multiple sclerosis (MS). In addition, an...

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Source

Identifiers

PMID: 23202984
DOI: 10.1016/j.jmgm.2012.11.002

Genes

TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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