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Article

Ligand-receptor binding revealed by the TNF family member TALL-1.

Nature - 1 May 2003

Liu Yingfang, Hong Xia, Kappler John, Jiang Ling, Zhang Rongguang, Xu Liangguo, Pan Cheol-Ho, Martin Wesley E, Murphy Robert C, Shu Hong-Bing, Dai Shaodong, Zhang Gongyi

Abstract excerpt

The tumour necrosis factor (TNF) ligand TALL-1 and its cognate receptors, BCMA, TACI and BAFF-R, were recently identified as members of the TNF superfamily, which are essential factors contributing to B-cell maturation. The functional, soluble fragment of TALL-1 (sTALL-1) forms a virus-like assembly for its proper function. Here we determine the crystal structures of sTALL-1 complexed with the extracellular...

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Identifiers

PMID: 12721620
DOI: 10.1038/nature01543

Genes

TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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