Article
Tumor necrosis factor-α gene polymorphisms in Korean patients with recurrent spontaneous abortion.
Reproductive sciences (Thousand Oaks, Calif.) - 1 Apr 2013
Lee Bo Eun, Jeon Young Joo, Shin Ji Eun, Kim Ji Hyang, Choi Dong Hee, Jung Yong Wook, Shim Sung Han, Lee Woo Sik, Kim Nam Keun
Abstract excerpt
The objective of this study was to investigate the contribution of the tumor necrosis factor-α (TNF-α) gene polymorphisms to recurrent spontaneous abortion (RSA). The study participants consisted of 357 Korean women with RSA and 236 fertile women controls. Four TNF-α gene variants of all participants were analyzed by polymerase chain reaction-restriction fragment length polymorphism assay. The TNF-α -1031T>C and...
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