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Article

Polymorphisms in tumor necrosis factor-alpha (-863C>A, -857C>T and +488G>A) are associated with idiopathic recurrent pregnancy loss in Korean women.

Human immunology - 1 Jun 2016

Jang Hyo Geun, Choi Youngsok, Kim Jung Oh, Jeon Young Joo, Rah HyungChul, Cho Sung Hwan, Kim Ji Hyang, Lee Woo Sik, Kim Nam Keun

Abstract excerpt

Polymorphisms in TNF-a have been reported as genetic risk factors for recurrent spontaneous abortion and TNF-α may be immunologically important. We therefore examined the contribution of several TNF-a mutations to this phenomenon. The study participants consisted of 388 patients with idiopathic recurrent pregnancy loss (RPL), which was diagnosed on the basis of at least two consecutive spontaneous abortions;...

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PMID: 27083536
DOI: 10.1016/j.humimm.2016.04.012

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TNF

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