Article
Association of tumor necrosis factor-α gene promoter polymorphisms (-308G/A, -238G/A) with recurrent spontaneous abortion: a meta-analysis.
Human immunology - 1 May 2012
Zhang Bingzhen, Liu Tiecheng, Wang Zhiping
Abstract excerpt
Tumor necrosis factor-α (TNF-α) gene promoter polymorphisms (-308G/A, -238G/A) have been associated with increased recurrent spontaneous abortion (RSA) risk, but the results of published articles are controversial. Hence, a meta-analysis was performed to assess the effect of TNF-α -308G/A, -238G/A polymorphisms on RSA risk. Heterogeneity testing and sensitivity analysis were performed using RevMan 5.0 software....
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