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Article

Integration-free induced pluripotent stem cells derived from retinitis pigmentosa patient for disease modeling.

Stem cells translational medicine - 1 Jun 2012

Jin Zi-Bing, Okamoto Satoshi, Xiang Ping, Takahashi Masayo

Abstract excerpt

We investigated retinitis pigmentosa (RP) caused by a mutation in the gene rhodopsin (RHO) with a patient-specific rod cell model generated from induced pluripotent stem cells (iPSCs) derived from an RP patient. To generate the iPSCs and to avoid the unpredictable side effects associated with ret...

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Source

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Identifiers

PMID: 23197854
DOI: 10.5966/sctm.2012-0005
PMCID: PMC3659711

Genes

RHO
RPE
KLF4
MYC
SOX2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23197854-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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