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Article

Modeling retinal degeneration using patient-specific induced pluripotent stem cells.

PloS one - 10 Feb 2011

Jin Zi-Bing, Okamoto Satoshi, Osakada Fumitaka, Homma Kohei, Assawachananont Juthaporn, Hirami Yasuhiko, Iwata Takeshi, Takahashi Masayo

Abstract excerpt

Retinitis pigmentosa (RP) is the most common inherited human eye disease resulting in night blindness and visual defects. It is well known that the disease is caused by rod photoreceptor degeneration; however, it remains incurable, due to the unavailability of disease-specific human photoreceptor cells for use in mechanistic studies and drug screening. We obtained fibroblast cells from five RP patients with...

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Source

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Identifiers

PMID: 21347327
DOI: 10.1371/journal.pone.0017084
PMCID: PMC3037398

Genes

PRPH2
RHO

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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