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Human mesenchymal stem cells possess different biological characteristics but do not change their therapeutic potential when cultured in serum free medium

4 Dec 2014

Abstract excerpt

INTRODUCTION: Mesenchymal stem cells (MSCs) are widely investigated in clinical researches to treat various diseases. Classic culture medium for MSCs, even for clinical use, contains fetal bovine serum. The serum-containing medium (SCM) seems a major obstacle for MSCs-related therapies due to the risk of contamination of infectious pathogens. Some studies showed that MSCs could be expanded in serum free medium...

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PMID: 25476802
DOI: 10.1186/scrt522

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