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Article

Double or compound sarcomere mutations in hypertrophic cardiomyopathy: a potential link to sudden death in the absence of conventional risk factors.

Heart rhythm - 1 Jan 2012

Maron Barry J, Maron Martin S, Semsarian Christopher

Abstract excerpt

BACKGROUND: Risk stratification strategies employing sarcomere gene mutational analysis have proved imprecise in identifying high-risk patients with hypertrophic cardiomyopathy (HCM). Therefore, additional genetic risk markers that reliably determine which patients are predisposed to sudden death are needed. OBJECTIVE: The objective of this study was to determine whether multiple disease-causing sarcomere...

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Share to Aged, 80 and over
Share to Cardiomyopathy, Hypertrophic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Death, Sudden, Cardiac

Share to DNA Mutational Analysis

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Source

Identifiers

PMID: 21839045
DOI: 10.1016/j.hrthm.2011.08.009

Genes

MYBPC3
TNNI3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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