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Article

p53 codon 72 polymorphism and coronary artery disease: evidence of interaction with ACP₁.

Medical science monitor : international medical journal of experimental and clinical research - 1 Dec 2012

Gloria-Bottini Fulvia, Banci Maria, Saccucci Patrizia, Neri Anna, Bottini Egidio, Magrini Andrea

Abstract excerpt

BACKGROUND: Common biological features between cancer and atherosclerosis suggest possible association of p53 with atherosclerotic diseases, but data on such a relationship are controversial, suggesting interactions with other variables. Acid phosphatase locus 1 (ACPACP₁) is a polymorphic gene that controls the synthesis of an enzyme involved in important metabolic functions. Since ACPACP₁ is associated with...

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Identifiers

PMID: 23197232
DOI: 10.12659/msm.883597
PMCID: PMC3560788

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CAD

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