Article
Coronary artery disease: evidence of interaction between PTPN22 and p53 genetic polymorphisms.
Cardiology - 1 Jan 2011
Saccucci P, Banci M, Amante A, Bottini E, Gloria-Bottini F
Abstract excerpt
OBJECTIVES: We recently reported an association between the PTPN22 genetic polymorphism and coronary artery disease (CAD) in nondiabetic subjects. Since recent studies suggest that p53 may be involved in coronary atherosclerosis, we have investigated a possible interaction between PTPN22 and p53 codon 72 genetic polymorphisms regarding their effects on susceptibility to CAD in nondiabetic subjects. METHODS: The...
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