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Article

Ezrin interacts with the SARS coronavirus Spike protein and restrains infection at the entry stage.

PloS one - 1 Jan 2012

Millet Jean Kaoru, Kien François, Cheung Chung-Yan, Siu Yu-Lam, Chan Wing-Lim, Li Huiying, Leung Hiu-Lan, Jaume Martial, Bruzzone Roberto, Peiris Joseph S Malik, Altmeyer Ralf Marius, Nal Béatrice

Abstract excerpt

BACKGROUND: Entry of Severe Acute Respiratory Syndrome coronavirus (SARS-CoV) and its envelope fusion with host cell membrane are controlled by a series of complex molecular mechanisms, largely dependent on the viral envelope glycoprotein Spike (S). There are still many unknowns on the implication of cellular factors that regulate the entry process. METHODOLOGY/PRINCIPAL FINDINGS: We performed a yeast two-hybrid...

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Identifiers

PMID: 23185364
DOI: 10.1371/journal.pone.0049566
PMCID: PMC3504146

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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