Article
MicroRNA expression profiles of LO2 cells expressing the wild-type and mutant HBx gene.
Molecular medicine reports - 1 Feb 2013
Fu Xiaoyu, Tan Deming, Hou Zhouhua, Hu Zhiliang, Liu Guozhen, Ouyang Yi, Liu Fei
Abstract excerpt
Hepatocellular carcinoma (HCC) is one of the most common malignancies worldwide. Although numerous studies have suggested the potentially oncogenic roles of wild‑type or mutant hepatitis B virus X (HBx) protein in hepatocarcinogenesis, their exact mechanism remains unclear. Increasing evidence suggests that microRNAs (miRNAs) play essential roles in embryogenesis, cell differentiation and carcinogenesis. This...
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