Article
A time-resolved immunoassay to measure serum antibodies to the rotavirus VP6 capsid protein.
Journal of virological methods - 1 Apr 2013
Kavanagh Owen, Zeng Xi-Lei, Ramani Sasirekha, Mukhopadhya Indrani, Crawford Sue E, Kang Gagandeep, Estes Mary K
Abstract excerpt
The rotavirus (RV) inner capsid protein VP6 is widely used to evaluate immune response during natural infection and in vaccine studies. Recombinant VP6 from the most prevalent circulating rotavirus strains in each subgroup (SG) identified in a birth cohort of children in southern India [SGII (G1P[8]) and SGI (G10P[11])] were produced. The purified proteins were used to measure VP6-specific antibodies in a...
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