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Article

Anti-VP6 VHH: An Experimental Treatment for Rotavirus A-Associated Disease.

PloS one - 1 Jan 2016

Maffey Lucía, Vega Celina G, Miño Samuel, Garaicoechea Lorena, Parreño Viviana

Abstract excerpt

Species A Rotaviruses (RVA) remain a leading cause of mortality in children under 5 years of age. Current treatment options are limited. We assessed the efficacy of two VP6-specific llama-derived heavy chain antibody fragments (VHH) -2KD1 and 3B2- as an oral prophylactic and therapeutic treatment against RVA-induced diarrhea in a neonatal mouse model inoculated with virulent murine RVA (ECw, G16P[16]I7). Joint...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 27603013
DOI: 10.1371/journal.pone.0162351
PMCID: PMC5014449

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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