Biogeographical distribution of gut microbiome composition and function is partially recapitulated by fecal transplantation into germ-free mice

Abstract excerpt

Fecal microbiota transplantation has been vital for establishing whether host phenotypes can be conferred through the microbiome. However, whether the existing microbial ecology along the mouse gastrointestinal tract can be recapitulated in germ-free mice colonized with stool remains unknown. We first identified microbes and their predicted functions specific to each of six intestinal regions in three cohorts of...

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