Linkage disequilibrium between TNF-α-308 G/A promoter and histocompatibility leukocyte antigen alleles in Han-nationality lung transplant recipients from Eastern China.

Abstract excerpt

OBJECTIVES: Genes encoding histocompatibility leukocyte antigen (HLA) and proinflammatory cytokines are involved in rejection after organ transplant. The authors explored the association between HLA alleles and the tumor necrosis factor (TNF)- α-308 G/A promoter region in lung transplant recipients of Han nationality from East China. They also evaluated the correlation between TNF-α-308 G/A and the onset of acute...

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