Article
IL2 and TNFA gene polymorphisms and the risk of graft-versus-host disease after allogeneic haematopoietic stem cell transplantation.
Scandinavian journal of immunology - 1 Dec 2007
Viel D O, Tsuneto L T, Sossai C R, Lieber S R, Marques S B D, Vigorito A C, Aranha F J P, de Brito Eid K A, Oliveira G B, Miranda E C M, de Souza C A, Visentainer J E L
Abstract excerpt
This study aimed to analyse the association of gene polymorphisms with the outcome of allogeneic haematopoietic stem cell transplantation. We studied 122 donor/recipient pairs who received HLA-identical transplants from siblings at the Universidade Estadual de Campinas, Brazil, between June 1996 and June 2006. Donor/recipient alleles for TNFA-238 and IL2-330/+166 single-nucleotide polymorphisms (SNP) were...
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